The Best Fall Road Trip Routes on the East Coast for Travel Nurses
Are you a travel nurse looking to make the most of fall on the East Coast? Whether you’re between contracts or enjoying a well-earned weekend off, autumn is the perfect season to hit the road and explore. With colorful foliage, crisp air, and charming towns, the East Coast offers travel nurses countless ways to recharge and adventure.
We believe that travel nursing should be more than a job, it’s a lifestyle full of discovery, balance, and unforgettable experiences. That’s why we’ve put together a list of the best fall road trip ideas for travel nurses working in the Eastern U.S.
1. Blue Ridge Parkway: Virginia to North Carolina
Perfect for: Travel nurses in Virginia, North Carolina, and nearby states
Route: Shenandoah National Park, VA ➝ Great Smoky Mountains, NC
Known as “America’s Favorite Drive,” the Blue Ridge Parkway is a must-see for nurses craving scenic drives and mountain views. The road winds through national parks, forests, and sleepy mountain towns that are picture-perfect in the fall. It’s especially accessible for nurses working in Roanoke, Asheville, or even D.C.
Nurse Tip: Many JNP travel nurse assignments in Virginia and North Carolina are just hours from this stunning route.
2. Kancamagus Highway, New Hampshire
Perfect for: New England-based travel nurses
Route: Lincoln ➝ Conway, NH
Known by locals as “The Kanc,” this 34-mile stretch through New Hampshire’s White Mountains offers some of the most vibrant fall foliage in the country. If you’re a travel nurse stationed in Boston, Maine, or Vermont, this is the ideal day trip to reconnect with nature.
Pro Tip: Take a quick hike to Sabbaday Falls for a refreshing break from the road.
3. Hudson Valley, New York
Perfect for: NYC-based travel nurses
Route: Tarrytown ➝ Hudson ➝ Catskills
Just a short drive from the city, the Hudson Valley is full of cozy towns, apple orchards, and craft markets, perfect for nurses wanting a peaceful escape. It’s also home to some of New York’s best fall foliage, wineries, and hiking trails.
Nurse-Friendly Highlight: Explore between shifts if you’re placed in the tri-state area with JNP.
4. Coastal Route 1: Maine to Massachusetts
Perfect for: Travel nurses along the Northeast Coast
Route: Portland, ME ➝ Salem, MA
If your assignment has you near the coast, take a scenic drive down U.S. Route 1. This trip combines the best of fall foliage and ocean views. Start with lobster rolls in Portland, wander through seaside villages, and end in Salem for some spooky seasonal fun.
October Bonus: Nurses love Salem during Halloween , street festivals, haunted tours, and witch history await.
5. The Berkshires, Massachusetts
Perfect for: Nurses needing rest and inspiration
Route: Lee ➝ North Adams, MA
The Berkshires offer rolling hills, historic towns, and cultural hotspots like MASS MoCA. Ideal for a long weekend between contracts, this area delivers peak foliage and peak relaxation.
Self-Care Alert: Take a solo trip here to unwind between demanding shifts.
6. Shenandoah Valley, Virginia
Perfect for: Travel nurses near D.C., Richmond, or Roanoke
Route: Front Royal ➝ Staunton, VA
Known for the Skyline Drive and abundant wineries, Shenandoah is ideal for fall. Whether you’re hiking, sipping wine, or just enjoying the views, it’s a tranquil and scenic reset.
Why Nurses Love It: Easy access + peaceful vibes = perfect nurse getaway.
Travel Tips for Fall Road Trips as a Travel Nurse
Whether you’re traveling solo or with fellow nurses, here’s how to make the most of your East Coast road trip:
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Plan around your shifts — Schedule days off or use gaps between assignments.
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Bring layers — Fall weather can shift quickly from warm to chilly.
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Pack light, travel smart — Stay flexible for spontaneous stops.
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Book ahead — Fall weekends can get busy, especially near foliage hotspots.
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